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Priyam Singh
11 April 2009 @ 04:46 pm

Well I think that the best person to share your problems is to confide with a stranger!!!!!!!!!!

What is your greatest accomplishment? What was the journey to get there?

 
 
Priyam Singh
24 March 2008 @ 05:30 pm
What is your greatest accomplishment? What was the journey to get there?
 Well My greatest accomplishment has been to grow more spiritual.............
Now i feel that i do understand God and religion in better terms..............
Analyzing Religion and science has been really great............
Above all It's been a long time since i was trying to know the meaning of Love and life.........
I got my faith,trust and confidence back from my true love..............So i think that has been my greatest accomplishment......................
 
 
Priyam Singh
29 February 2008 @ 04:20 pm
What is one thing you struggle to describe?
 
 
 
 
Priyam Singh
21 February 2008 @ 07:53 pm
  Well I think That There is no perfect candidate for the presedential elections in the present time which is unfortunately an inconvenient truth................
Bcoz in My view the perfect President has to be Dead honest................Patriotic..............Shouldn't be much swayed away by the materialism and passion...................
Lastly he/she has to be born spiritual.................
And i think It's difficult to find such kind of a person in The present time............
Regards,
Priyam Singh.

Health: Can Exercise Make You Smarter?



Exercise does more than build muscles and help prevent heart disease. New science shows that it


also boosts brainpower—and may offer hope in the battle against Alzheimer's.



By Mary Carmichael



Newsweek



March 26, 2007 issue - The stereotype of the "dumb jock" has never sounded right to Charles Hillman. A jock


himself, he plays hockey four times a week, but when he isn't body-checking his opponents on the ice, he's giving


his mind a comparable workout in his neuroscience and kinesiology lab at the University of Illinois. Nearly every


semester in his classroom, he says, students on the women's cross-country team set the curve on his exams. So


recently he started wondering if there was a vital and overlooked link between brawn and brains—if long hours at


the gym could somehow build up not just muscles, but minds. With colleagues, he rounded up 259 Illinois third


and fifth graders, measured their body-mass index and put them through classic PE routines: the "sit-and-reach,"


a brisk run and timed push-ups and sit-ups. Then he checked their physical abilities against their math and


reading scores on a statewide standardized test. Sure enough, on the whole, the kids with the fittest bodies were


the ones with the fittest brains, even when factors such as socioeconomic status were taken into account. Sports,


Hillman concluded, might indeed be boosting the students' intellect—and also, as long as he didn't "take a puck to


the head," his own.


Hillman's study, which will be published later this year, isn't definitive enough to stand alone. But it doesn't have


to: it's part of a recent and rapidly growing movement in science showing that exercise can make people smarter.


Last week, in a landmark paper, researchers announced that they had coaxed the human brain into growing new


nerve cells, a process that for decades had been thought impossible, simply by putting subjects on a three-month


aerobic-workout regimen. Other scientists have found that vigorous exercise can cause older nerve cells to form


dense, interconnected webs that make the brain run faster and more efficiently. And there are clues that physical


activity can stave off the beginnings of Alzheimer's disease, ADHD and other cognitive disorders. No matter your


age, it seems, a strong, active body is crucial for building a strong, active mind.


Scientists have always suspected as much, although they have not been able to prove it. The idea of the "scholarathlete"


isn't just a marketing ploy dreamed up by the NCAA; it goes back to the culture of ancient Greece, in


which "fitness was almost as important as learning itself," says Harvard psychiatrist John Ratey. The Greeks, he


adds, were clued into "the mind-body connection." And they probably intuited a basic principle that Western


researchers also figured out long ago: aerobic exercise helps the heart pump more blood to the brain, along with


the rest of the body. More blood means more oxygen, and thus better-nourished brain cells. For decades, that has


been the only link between athletic and mental prowess that science has been able to demonstrate with any


degree of certainty. "People have been slow to grasp that exercise can really affect cognition," says Hillman, "just


as it affects muscles."


Now, however, armed with brain-scanning tools and a sophisticated understanding of biochemistry, researchers


are realizing that the mental effects of exercise are far more profound and complex than they once thought. The


process starts in the muscles. Every time a bicep or quad contracts and releases, it sends out chemicals, including


a protein called IGF-1 that travels through the bloodstream, across the blood-brain barrier and into the brain


itself. There, IGF-1 takes on the role of foreman in the body's neurotransmitter factory. It issues orders to ramp


up production of several chemicals, including one called brain-derived neurotrophic factor, or BDNF. Ratey, author


of the upcoming book "Spark: The Revolutionary New Science of Exercise and the Brain," calls this molecule


"Miracle-Gro for the brain." It fuels almost all the activities that lead to higher thought.


With regular exercise, the body builds up its levels of BDNF, and the brain's nerve cells start to branch out, join


together and communicate with each other in new ways. This is the process that underlies learning: every change


in the junctions between brain cells signifies a new fact or skill that's been picked up and stowed away for future


use. BDNF makes that process possible. Brains with more of it have a greater capacity for knowledge. On the


other hand, says UCLA neuroscientist Fernando Gómez-Pinilla, a brain that's low on BDNF shuts itself off to new


information. In his experiments, rats were put through weeks of running on a wheel, a workout that increased


their BDNF levels. Gómez-Pinilla left half of the animals alone; in the other half, he blocked the chemical's effects


with a drug. Then he subjected both groups of athletic rats to a test of wits, encouraging them to find an object


that was hidden underwater. The first group easily pinpointed its location, but the second, BDNF-deprived group


wasn't nearly as quick or sharp. Nature has conducted a similar experiment on humans. In unlucky people with a


faulty variant of the gene that makes BDNF, the brain has trouble both creating new memories and calling up old


ones.


Most people maintain fairly constant levels of BDNF in adulthood. But as they age, their individual neurons slowly


start to die off. Until the mid-'90s, scientists thought the loss was permanent—that the brain couldn't make new


nerve cells to replace the dead ones. But animal studies over the last decade have overturned that assumption,


showing that "neurogenesis" in some parts of the brain can be induced easily with exercise. Last week's study,


published in the Proceedings of the National Academy of Sciences, extended that principle to humans for the first


time. After working out for three months, all the subjects appeared to sprout new neurons; those who gained the


most in cardiovascular fitness also grew the most nerve cells. This, too, might be BDNF at work, transforming stem


cells into full-grown, functional neurons. "It was extremely exciting to see this exercise effect in humans for the


first time," says Scott Small, a Columbia University Medical Center neurologist who coauthored the study with Salk


Institute neurobiologist Fred Gage. "In terms of trying to understand what it means, the field is just exploding."


The first step toward that understanding is to figure out exactly where the new brain cells are growing—and


whether that is a part of the brain that needs to be rejuvenated. In Small and Gage's experiment, the new


neurons created by exercise cropped up in only one place: the dentate gyrus of the hippocampus, an area that


controls learning and memory. This region, tucked under the temporal lobes, helps the brain match names to faces


—one of the first skills to erode as we age. Fortunately, the hippocampus is especially responsive to BDNF's


effects, and exercise seems to restore it to a healthier, "younger" state. "It's not just a matter of slowing down


the aging process," says Arthur Kramer, a psychologist at the University of Illinois. "It's a matter of reversing it."


Kramer's work also has implications for the frontal lobes, the seat of "executive functioning"—a type of higher


thought that entails decision-making, multitasking and planning ahead. With scanning technology, he has found


that exercise causes the frontal lobes to increase in size. And in dozens of previous studies of men and women in


their 60s and 70s, brisk walking and other aero-bic workouts have yielded improvements in executive functioning.


Subjects have fared better on psychological tests, answering questions more accurately and quickly. With the new


brain studies, researchers can now begin to explain why.


As far as scientists know, new neurons can't grow throughout the rest of the brain. But other regions benefit from


exercise in many secondary ways. Blood volume, like brain volume, increases with exercise, says Small: "Wherever


you have the birth of new brain cells, you have the birth of new capillaries." Active adults have less inflammation


in the brain. They also have fewer "little bitty strokes that can impair cognition without the person even knowing,"


says University of California, San Francisco, neuroscientist Kristine Yaffe. Still other researchers have found that


athletes have more astrocytes, or cells that support neurons and mop up neurotransmitters after they're used to


send messages from cell to cell. And even the levels of those neurotransmitters are higher in people who exercise


frequently. "Dopamine, serotonin, norepinephrine—all of these are elevated after a bout of exercise," says Ratey.


"So having a workout will help with focus, calming down, impulsivity—it's like taking a little bit of Prozac and a


"Miracle-Gro for the brain." It fuels almost all the activities that lead to higher thought.


With regular exercise, the body builds up its levels of BDNF, and the brain's nerve cells start to branch out, join


together and communicate with each other in new ways. This is the process that underlies learning: every change


in the junctions between brain cells signifies a new fact or skill that's been picked up and stowed away for future


use. BDNF makes that process possible. Brains with more of it have a greater capacity for knowledge. On the


other hand, says UCLA neuroscientist Fernando Gómez-Pinilla, a brain that's low on BDNF shuts itself off to new


information. In his experiments, rats were put through weeks of running on a wheel, a workout that increased


their BDNF levels. Gómez-Pinilla left half of the animals alone; in the other half, he blocked the chemical's effects


with a drug. Then he subjected both groups of athletic rats to a test of wits, encouraging them to find an object


that was hidden underwater. The first group easily pinpointed its location, but the second, BDNF-deprived group


wasn't nearly as quick or sharp. Nature has conducted a similar experiment on humans. In unlucky people with a


faulty variant of the gene that makes BDNF, the brain has trouble both creating new memories and calling up old


ones.


Most people maintain fairly constant levels of BDNF in adulthood. But as they age, their individual neurons slowly


start to die off. Until the mid-'90s, scientists thought the loss was permanent—that the brain couldn't make new


nerve cells to replace the dead ones. But animal studies over the last decade have overturned that assumption,


showing that "neurogenesis" in some parts of the brain can be induced easily with exercise. Last week's study,


published in the Proceedings of the National Academy of Sciences, extended that principle to humans for the first


time. After working out for three months, all the subjects appeared to sprout new neurons; those who gained the


most in cardiovascular fitness also grew the most nerve cells. This, too, might be BDNF at work, transforming stem


cells into full-grown, functional neurons. "It was extremely exciting to see this exercise effect in humans for the


first time," says Scott Small, a Columbia University Medical Center neurologist who coauthored the study with Salk


Institute neurobiologist Fred Gage. "In terms of trying to understand what it means, the field is just exploding."


The first step toward that understanding is to figure out exactly where the new brain cells are growing—and


whether that is a part of the brain that needs to be rejuvenated. In Small and Gage's experiment, the new


neurons created by exercise cropped up in only one place: the dentate gyrus of the hippocampus, an area that


controls learning and memory. This region, tucked under the temporal lobes, helps the brain match names to faces


—one of the first skills to erode as we age. Fortunately, the hippocampus is especially responsive to BDNF's


effects, and exercise seems to restore it to a healthier, "younger" state. "It's not just a matter of slowing down


the aging process," says Arthur Kramer, a psychologist at the University of Illinois. "It's a matter of reversing it."


Kramer's work also has implications for the frontal lobes, the seat of "executive functioning"—a type of higher


thought that entails decision-making, multitasking and planning ahead. With scanning technology, he has found


that exercise causes the frontal lobes to increase in size. And in dozens of previous studies of men and women in


their 60s and 70s, brisk walking and other aero-bic workouts have yielded improvements in executive functioning.


Subjects have fared better on psychological tests, answering questions more accurately and quickly. With the new


brain studies, researchers can now begin to explain why.


As far as scientists know, new neurons can't grow throughout the rest of the brain. But other regions benefit from


exercise in many secondary ways. Blood volume, like brain volume, increases with exercise, says Small: "Wherever


you have the birth of new brain cells, you have the birth of new capillaries." Active adults have less inflammation


in the brain. They also have fewer "little bitty strokes that can impair cognition without the person even knowing,"


says University of California, San Francisco, neuroscientist Kristine Yaffe. Still other researchers have found that


athletes have more astrocytes, or cells that support neurons and mop up neurotransmitters after they're used to


send messages from cell to cell. And even the levels of those neurotransmitters are higher in people who exercise


frequently. "Dopamine, serotonin, norepinephrine—all of these are elevated after a bout of exercise," says Ratey.


"So having a workout will help with focus, calming down, impulsivity—it's like taking a little bit of Prozac and a


"Miracle-Gro for the brain." It fuels almost all the activities that lead to higher thought.


With regular exercise, the body builds up its levels of BDNF, and the brain's nerve cells start to branch out, join


together and communicate with each other in new ways. This is the process that underlies learning: every change


in the junctions between brain cells signifies a new fact or skill that's been picked up and stowed away for future


use. BDNF makes that process possible. Brains with more of it have a greater capacity for knowledge. On the


other hand, says UCLA neuroscientist Fernando Gómez-Pinilla, a brain that's low on BDNF shuts itself off to new


information. In his experiments, rats were put through weeks of running on a wheel, a workout that increased


their BDNF levels. Gómez-Pinilla left half of the animals alone; in the other half, he blocked the chemical's effects


with a drug. Then he subjected both groups of athletic rats to a test of wits, encouraging them to find an object


that was hidden underwater. The first group easily pinpointed its location, but the second, BDNF-deprived group


wasn't nearly as quick or sharp. Nature has conducted a similar experiment on humans. In unlucky people with a


faulty variant of the gene that makes BDNF, the brain has trouble both creating new memories and calling up old


ones.


Most people maintain fairly constant levels of BDNF in adulthood. But as they age, their individual neurons slowly


start to die off. Until the mid-'90s, scientists thought the loss was permanent—that the brain couldn't make new


nerve cells to replace the dead ones. But animal studies over the last decade have overturned that assumption,


showing that "neurogenesis" in some parts of the brain can be induced easily with exercise. Last week's study,


published in the Proceedings of the National Academy of Sciences, extended that principle to humans for the first


time. After working out for three months, all the subjects appeared to sprout new neurons; those who gained the


most in cardiovascular fitness also grew the most nerve cells. This, too, might be BDNF at work, transforming stem


cells into full-grown, functional neurons. "It was extremely exciting to see this exercise effect in humans for the


first time," says Scott Small, a Columbia University Medical Center neurologist who coauthored the study with Salk


Institute neurobiologist Fred Gage. "In terms of trying to understand what it means, the field is just exploding."


The first step toward that understanding is to figure out exactly where the new brain cells are growing—and


whether that is a part of the brain that needs to be rejuvenated. In Small and Gage's experiment, the new


neurons created by exercise cropped up in only one place: the dentate gyrus of the hippocampus, an area that


controls learning and memory. This region, tucked under the temporal lobes, helps the brain match names to faces


—one of the first skills to erode as we age. Fortunately, the hippocampus is especially responsive to BDNF's


effects, and exercise seems to restore it to a healthier, "younger" state. "It's not just a matter of slowing down


the aging process," says Arthur Kramer, a psychologist at the University of Illinois. "It's a matter of reversing it."


Kramer's work also has implications for the frontal lobes, the seat of "executive functioning"—a type of higher


thought that entails decision-making, multitasking and planning ahead. With scanning technology, he has found


that exercise causes the frontal lobes to increase in size. And in dozens of previous studies of men and women in


their 60s and 70s, brisk walking and other aero-bic workouts have yielded improvements in executive functioning.


Subjects have fared better on psychological tests, answering questions more accurately and quickly. With the new


brain studies, researchers can now begin to explain why.


As far as scientists know, new neurons can't grow throughout the rest of the brain. But other regions benefit from


exercise in many secondary ways. Blood volume, like brain volume, increases with exercise, says Small: "Wherever


you have the birth of new brain cells, you have the birth of new capillaries." Active adults have less inflammation


in the brain. They also have fewer "little bitty strokes that can impair cognition without the person even knowing,"


says University of California, San Francisco, neuroscientist Kristine Yaffe. Still other researchers have found that


athletes have more astrocytes, or cells that support neurons and mop up neurotransmitters after they're used to


send messages from cell to cell. And even the levels of those neurotransmitters are higher in people who exercise


frequently. "Dopamine, serotonin, norepinephrine—all of these are elevated after a bout of exercise," says Ratey.


"So having a workout will help with focus, calming down, impulsivity—it's like taking a little bit of Prozac and a


little bit of Ritalin."


Unlike neurogenesis, which can take weeks to occur, most of these additional effects appear almost immediately.


Get off the treadmill after a half-hour workout, says Hillman, and "within 48 minutes" your brain will be in better


shape. But alas, these benefits are somewhat transient. Like weight, mental fitness has to be maintained. New


neurons, and the connections between them, will stick around for years, but within a month of inactivity, "the


astrocytes shrink down again, and then the neurons don't function as well anymore," says William Greenough, a


psychologist at the University of Illinois. Let your body go, then, and your brain will follow.


To keep the effects, you've got to keep working out. "If you're thinking that by exercising at age 20 you're going


to have some effect on what you're like at age 70," Greenough adds, you'd better be willing to commit to 50 years


of hitting the gym.


Unless, that is, you're a kid. Most studies of exercise and cognition have focused on older people—the folks who


are just starting to worry that their minds aren't what they used to be—but the effects of physical exertion on the


brain aren't limited to that group at all. In fact, in young children, they're even more potent. Exercise probably has


"a more long-lasting effect on brains that are still developing," says Phil Tomporowski, a professor of exercise


science at the University of Georgia. In kids, as in adults, the hippocampus reaps many benefits from exercise.


This won't surprise parents of kids with ADHD, many of whom already use physical activity as a substitute or


supplement for drugs. In children with the disorder, the hippocampus is enlarged, and it may be wired to the rest


of the brain in abnormal ways that affect its function.


But a good workout, or for that matter a boisterous session of kickball, can also have much more widespread


effects on children's brains. Until about 20, kids don't have fully developed frontal lobes, so they "recruit" other


parts of the brain to perform necessary functions, including those involved in learning. In Hillman's look at thirdand


fifth-grade PE students, exercise sped up not just executive functioning, but a broad variety of skills ranging


from math to logic to reading, all of which rope in many regions of the brain. "In kids you have a tremendous


amount of growing brain tissue, particularly in the frontal lobe," says Tomporowski. "So we can't just break it


down to hippocampal function in them. Exactly what else is going on in there, I don't think anybody knows."


With that science in mind, many educators are now pushing for an overhaul of physical education in public schools.


Teachers can ensure their students' success in other subjects, they argue, by making PE longer and more focused


on brain-strengthening cardiovascular exercise. Inspired by Hillman's work, Kentucky State Sen. Katie Stine


recently proposed a bill making a daily half hour of PE mandatory for kids up to eighth grade. It passed the Senate


last month. And at schools in Naperville, Ill., students with poor verbal skills have started taking PE immediately


before reading class. Their report cards, says Ratey, are already looking better.


The hope of educators isn't just that Johnny and Susie will do better on the SAT. There's a long-term goal as well.


If kids develop a love of sport early in life, they're more likely to grow into active adults. And if they do, they may


avoid a fate their grandparents are currently facing: a slow slide into mild cognitive impairment, followed by


Alzheimer's. Gómez-Pinilla says that Americans' lazy lifestyles may be contributing to their high rates of the


disease. Humans have evolved, he notes, to thrive on physical activity; without it, "our brains aren't doing what


they're supposed to," and they go awry. Early studies suggest that people who exercise at least a few times a


week tend to develop Alzheimer's less often and later than their more sedentary counterparts. There are clues at


the level of the brain as well: one of the disease's first targets is the hippocampus.


More controversial is the proposal that exercise might slow the progression of Alzheimer's once it has taken hold.


"By the time somebody has fairly well-developed Alzheimer's, it's probably too late," says Yaffe. "It's going to be


difficult to get them into an exercise program at that point, and the damage may already be done." There's a grain
http://www.msnbc.msn.com/id/17662246/site/newsweek/page/2/

 


of hope, however, to be found in animal studies. In mice that develop a disease that resembles Alzheimer's, a type


of plaque similar to what's found in people builds up in the brain. Carl Cotman, a neuroscientist at the University


of California, Irvine, examined those mice in 2005 and found that those who spent more time running on wheels


fared better on memory tests. They also had lower levels of plaque in their brains, he says, possibly "because


exercise caused them to produce less plaque and clear more of it."


That gives rise to the question: if exercise is such good medicine, could scientists someday distill its brainpowering


effects into chemical form—a sort of "workout in a pill"? The result might end up resembling many of the


drugs that scientists are currently developing to bolster memory in Alzheimer's patients. It would also surely


appeal to people who aren't willing to drag themselves to the gym every other day. "There's a resistance to


maintaining an exercise program, since it involves a lot of work. People just don't feel like it," says Ratey. "They're,


like, 'I want it done fast, and I want it done now, and why should I have to labor over the treadmill?' " Small, the


Columbia researcher, says many of his lab colleagues have started working out because of his study results. But,


he adds, for his own part, he "would much rather find that biochemical link and think about how we might be able


to reproduce the effect for the couch potatoes."


Before that can happen—way before that can happen—scientists will have to answer a number of nagging


questions that remain. Chief among them is why some forms of exercise affect the brain far more than others.


Most researchers have focused on aerobic exercise, "and they've ignored strength training" in the process, says


Carole Lewis, a physical therapist and coauthor of the new book "Age-Defying Fitness." So far, though, for reasons


that no one really understands, the few studies that have examined stretching, toning and weight lifting have


found little to no effect on cognition. Researchers also don't have a clear idea of how much exercise is too much.


"There are very good rules for how many hours a day you should work out, and how many days a week, and what


kinds of rest periods you should take—but that's all with respect to the rest of your body," says Greenough. "As


for the brain, it's just not known, and we need studies like that."


Finally, there's the question that's been dogging Charles Hillman since he first picked up a hockey stick: why, if


jocks on average have more capable brains than the rest of the public, do they have an unfair reputation for being


dumb? Why does a term like "scholar-athlete," which would have made so much sense to the ancient Greeks, get


snickered at today? The reason, says Hillman, is found not in science but in common sense: some of our schools


have failed young athletes by cutting them too much slack. "A lot of it comes from schools' giving them an easy


road," he says. "Kids get this wholly inaccurate label because they're good at sports, and then too much emphasis


is placed on their physical abilities at the expense of their mental abilities." Having a big, gorgeous, healthy brain


isn't enough, of course; it also has to be full. For that, kids have to hit the library as well as the gym. "You can


optimize your brain to learn," says Ratey, "but then you have to be in an environment where you can do that—and


you have to want it." Sometimes, it's the "scholar," not the "athlete," who counts.


 

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Priyam Singh

When was the last time you surprised yourself?



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